Newly discovered RNA steers brain development (Harvard Medical School study)

“FINDINGS:
A newly discovered class of RNA molecules helps elucidate the long-standing scientific question of how a person’s external experiences turn on the genes that over time help shape the connections among cells that make up the human brain. Called enhancer RNAs, these molecules operate globally throughout the genome within neurons.”

“New research from the lab of Michael Greenberg, Nathan Marsh Pusey professor and chair of neurobiology at HMS, in collaboration with bioinformatics specialist and neuroscientist Gabriel Kreiman, assistant professor of ophthalmology at Children’s Hospital Boston, has found that a particular set of RNA molecules widely considered to be no more than a genomic oddity are actually major players in brain development—and are essential for regulating the process by which neurons absorb the outside world into their genetic machinery.”

http://hms.harvard.edu/public/news/2010/041410_greenberg.html

 

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